Reona Kisaragi/Relationships

Hiroshi Yuuki
They seem to be in good terms, but Hiro is always surprised of how weird she is with her obsession for realism in games. She supports Hiro, but as shown in Episode 5 is capable of using her good looks to manipulate him to continue playing Kiwame Quest, when he was ready to quit. It appears that Hiro has feelings for her, but its not clear if she likes him back. Though it appears that she is using Hiro so she could take his revenge

Soichiro Kamui
When they met, Reona asked him if they could go out on a date, but Kamui rejected her saying he is not into girl with tits like a Holstein cow, leaving her angry and seeking revenge.